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ISRN Oncology
Volume 2012 (2012), Article ID 902178, 6 pages
http://dx.doi.org/10.5402/2012/902178
Review Article

The Role of Radiotherapy and Chemotherapy in the Treatment of Primary Adult High Grade Gliomas: Assessment of Patients for These Treatment Approaches and the Common Immediate Side Effects

1Department of Internal Medicine, College of Medical Sciences, University of Calabar, PMB 1278, Nigeria
2Department of Paediatrics, College of Medical Sciences, University of Calabar, PMB 1278, Nigeria

Received 11 October 2012; Accepted 6 November 2012

Academic Editors: H. Al-Ali, J. Bentel, N. Fujimoto, and L. Mutti

Copyright © 2012 E. E. Philip-Ephraim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Gliomas are the commonest primary brain tumours in adults. They are usually classified and graded according to the criteria by the World Health Organisation. High-grade gliomas are the most malignant primary brain tumours. Conventional therapies include surgery, radiotherapy, and chemotherapy. The tumours often demonstrate high levels of resistance to these conventional therapies, and in spite of treatment advances the prognosis remains poor.