Research Article

Comparison of Gene Expression Profiling in Sarcomas and Mesenchymal Stem Cells Identifies Tumorigenic Pathways in Chemically Induced Rat Sarcoma Model

Figure 3

The ratio of 𝑔 scale signal intensity of cell adhesion and extracellular matrix interaction molecules in both sarcomas compared to MSCs are shown. Integrins and their ligands CAMS were strongly expressed in MSCs, especially differential expression of CAMs between sarcomas and MSCs was significant. Matrix metalloproteinase 2 and 9 also showed higher expression in MSCs.
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