Table 1: Administration schedule for each cohort of rapid infusion rituximab.

Rituximab 375 mg/m2 intravenously in 250 mL normal saline

Cycle 1
 10 mL/h (first 1 hour) → 50 mL/h (second 1 hour) → 100 mL/h (until end of treatment)
Cycle 2–8
 Cohort 1 50 mL/h (constant infusion, until end of treatment)
 Cohort 2100 mL/h (constant infusion, until end of treatment)
 Cohort 3150 mL/h (constant infusion, until end of treatment)
 Cohort 4200 mL/h (constant infusion, until end of treatment)
 Cohort 5250 mL/h (constant infusion, until end of treatment)
 Cohort 6300 mL/h (constant infusion, until end of treatment)