Table 3: Adverse events.

G1G2G3G4Total

Leukocytopenia1 6 1 6 1 6 0 0 3 17
Neutropenia1 6 1 6 0 0 1 6 317
Anemia211 0 0 0 0 0 0 2 11
Infusion reaction422 0 0 0 0 0 0 4 22
Conduction disorder1 6 0 0 0 0 0 0 1 6
Ventricular arrhythmia211 0 0 0 0 0 0 2 11
Malaise317 0 0 0 0 0 0 317
Hypotension1 6 0 0 0 0 0 0 1 6
Pharyngitis 211 1 6 0 0 0 0 317
Bronchitis0 0 1 6 0 0 0 0 1 6
Herpes zoster infection0 0 1 6 0 0 0 0 1 6
Diarrhea1 6 1 6 0 0 0 0 2 11
AST increased317 0 0 0 0 0 0 3 17
ALT increased211 0 0 0 0 0 0 2 11
Nausea 1 6 0 0 0 0 0 0 1 6
Palpitations 1 6 0 0 0 0 0 0 1 6
Allergic rhinitis 1 6 0 0 0 0 0 0 1 6
Constipation 1 6 1 6 0 0 0 0 2 11
Insomnia 211 0 0 0 0 0 0 2 11
Peripheral neuropathy 211 0 0 0 0 0 0 2 11
Creatinine increased 1 6 0 0 0 0 0 0 1 6
Acne 0 0 1 6 0 0 0 0 1 6
Anorexia 1 6 0 0 0 0 0 0 1 6

AST: aspartate aminotransferase; ALT: alanine aminotransferase.