Table 3: Downregulated pathways in T1 breast cancer tumors compared to T2 tumors.

TermGenesCount% valueBenjamini

Neurotrophin signaling pathway (KEGG_PATHWAY)YWHAZ, GRB2, RAC1, YWHAQ, FRS252.84.2 9.8
p38 MAPK Signaling Pathway (BIOCARTA)GRB2, RAC1, MKNK131.75.0 9.8
Prion diseases (KEGG_PATHWAY)C1QA, C1QB, C1QC31.75.3 9.1
Jak-STAT signaling pathway (KEGG_PATHWAY)OSM, IFNA2, GRB2, IL10RA, IL4R52.88.1 9.2
Systemic lupus erythematosus (KEGG_PATHWAY)C1QA, C1QB, HLA-DPB1, C1QC42.28.7 8.7
Toll-like receptor signaling pathway (KEGG_PATHWAY)IFNA2, MYD88, TICAM1, RAC142.29.1 8.2