Table 2: Effect of solvent for the synthesis of 2-substituted-4,6-diarylpyrimidinea.

EntrySolventYield (%)

1None20
2H2O30
3NMP68
4DMSO75
5DMF90

aReaction conditions: chalcone (0.002 mol), SBT (0.0022 mol), heterocyclic secondary amine (0.0024 mol), and ZnO catalyst (15 mol%) in DMF (10 mL) at 100°C temperature for 6 h.