Table 2: Antiviral activity of compounds 6a6d.

Anti-JEV in vitro Anti-HSV-1 in vitro
Compound. numberCT50 ( 𝜇 g/mL) EC50 ( 𝜇 g/mL)TIInhibition (%)EC50 ( 𝜇 g/mL)TIInhibition (%)

6a50012504102500210
6b50012504102500210
6c2507.832501250223
6d50012504152500220

CT50: 50% cytotoxic concentration; EC50: 50% effective concentration; TI: therapeutic index.