Table 2: (a) Genotype frequencies of the A(-1364)C-AQP5 polymorphism in patients with endolymphatic hydrops (EH), familial Menière’s disease (FMD), and Menière’s disease (MD) and in healthy controls. (b) Genotype frequencies of the A(-1364)C-AQP5 polymorphism in patients with different grades of EH and Menière’s disease according to AAO-HNS.
(a)

Genotypes/alleles/entitiesAAAC CC valueAC value
(%) (%) (%) (%) (%)

EH8 1 0 0.3521710.334
(88.9)(11.1)0(94.4)(5.6)

MD23 12 1 0.39158140.498
(63.9)(33.3)(2.8)(80.6)(19.4)

FMD37 11 3 0.042 * 85170.884
(72.5)(21.6)(5.9)(82.7)(17.3)

Controls202 87 3 49193
(69.9)(30)(1)84.1(15.9)

values refer to statistical significance ( ) of genotype frequencies within the particular groups of EH, MD, and FMD. value of CC in the FMD group (0.042) is considered as statistically significant.
(b)

Genotypes/stadiumAAACCCAll

EH8109
Grade 17108
Grade 2206026
Grade 33015345
grade 43115