Table 1: CXC Chemokine ligands and their receptors.

Systematic nameCXC ChemokineChemokine receptorFunction
HumanMouse

ELR + chemokines
 CXCL1MGSA- /GRO- GRO/MIP-2CXCR2 > CXCR1P
 CXCL2MGSA- /GRO- GRO/MIP-2CXCR2P
 CXCL3MGSA- /GRO- GRO/MIP-2CXCR2P
 CXCL5ENA-78GCP2/LIX?CXCR2P
 CXCL6GCP-2GCP2/LIX?CXCR1, CXCR2P
 CXCL7NAP-2CRA-a,bCXCR2P
 CXCL8IL-8UnknownCXCR1, CXCR2P

ELR − chemokines
 CXCL4PF-4PF-4CXCR3A and BA/S
 CXCL9MigMigCXCR3A
 CXCL10IP-10IP10CRG2CXCR3A
 CXCL11I-TACI-TACCXCR3A
 CXCL12SDF-1 / SDF1/PBSFCXCR4, CXCR7M, P
 CXCL13BCA-1BLCCXCR5?
 CXCL14BRAKBRAK (BMAC)?A/N/S
 CXCL16SR-PSOXCXCL16CXCR6NT/S

A: angiostatic, M: metastatic, N: NK cell regulation, NT: NKT cell regulation, P: tumor progression, S: tumor suppression.