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ISRN Pathology
Volume 2011 (2011), Article ID 267145, 7 pages
http://dx.doi.org/10.5402/2011/267145
Research Article

Transmucosal Fine Needle Aspiration of Oral and Pharyngeal Lesions

1Department of Pathology, State University of New York, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
2Department of Otolaryngology, State University of New York, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA

Received 21 March 2011; Accepted 24 April 2011

Academic Editor: J. A. Jimenez-Heffernan

Copyright © 2011 Fang-Ming Deng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Fine Needle aspiration (FNA) studies of oropharyngeal lesions are few and limited. We retrospectively reviewed cytologic diagnosis and cytohistologic correlation of 28 cases of FNAs of oropharyngeal lesions. Cytologically, 11 cases were diagnosed as malignant/suspicious and 17 cases as benign. Ten of these cases diagnosed as malignant/suspicious correlated with the subsequent histological diagnosis or were compatible with previous histological diagnoses. One case categorized as suspicious for malignancy revealed pleomorphic adenoma with extensive squamous metaplasia. Of the 17 cases diagnosed as benign by cytology, 11 correlated with the subsequent histological diagnosis. The remaining 6 cytologically benign cases were considered clinically benign, and there was no histological followup. Clinical followup on these 6 patients did not reveal any evidence of disease. The sensitivity, specificity, and accuracy of malignant diagnosis were 100%, 95%, and 97%. FNA biopsy may be used as the first line of investigation in evaluation of oropharyngeal lesions.