Research Article

Snail Protein Expression as a Hallmark of Gastric Carcinoma in Biopsy Samples

Table 6

Correlation between Snail expression and E-cadherin, vimentin expression in carcinoma biopsy samples.

Differentiation Snail expression in carcinomaTotalP
Negative (<10)Low (10–20)High (>20)165

WellE-cadherin360.031
 Negative (0–10%)03 (8%)20 (56%)23
 Positive (>10%)1 (3%)6 (16%)6 (17%)13
Vimentin360.025
 Negative (0–10%)1 (3%)4 (11%)3 (8%)8
 Positive (>10%)05 (14%)23 (64%)28

ModeratelyE-cadherin480.039
 Negative (0–10%)05 (10%)30 (63%)35
 Positive (>10%)08 (17%)5 (10%)13
Vimentin480.032
 Negative (0–10%)06 (12%)3 (6%)9
 Positive (>10%)07 (15%)32 (67%)39

PoorlyE-cadherin510.019
 Negative (0–10%)04 (8%)41 (80%)45
 Positive (>10%)03 (6%)3 (6%)6
Vimentin510.023
 Negative (0–10%)02 (4%)4 (8%)6
 Positive (>10%)05 (10%)40 (78%)45 

Signet-ring cellE-cadherin300.042
 Negative (0–10%)3 (10%)5 (17%)10 (33%)18
 Positive (>10%)6 (20%)5 (17%)1 (3%)12
Vimentin300.044
 Negative (0–10%)7 (23%)6 (20%)013
 Positive (>10%)2 (7%)4 (14%)11 (36%)17