Table 2: Mean pharmacokinetic profile ( ).

Drug name AUC0–t AUC0–∞

IR13.812
(1.072)
2.25
(0.273)
45.591
(6.331)
2.188
(0.175)
0.318
(0.024)
47.621
(6.242)

SR14.178
(0.701)
5.00
(1.095)
117.843
(14.537)
4.772
(0.303)
0.145
(0.008)
122.620
(14.552)

aImmediate release (IR) tablets.
bSustained release (SR) tablets.
Results represent the mean of replicate determination with the standard deviation given in parenthesis.
Significantly higher than IR tablets.
Significantly lower than IR tablets.