738432.fig.0010
Figure 10: Graphic representation of the two main shedding concepts: (a) the enclosed drug is released to the ECF after PEG polymers have unmasked the liposome upon arrival to the tumoral site and (b) targeting ligands are revealed after their polymer coating has been shed at the moment liposomes arrive to their target; now they are able to interact with appropriate formations on the cell’s surface.