Table 3: Order of drug release of various formulations determined by the regression coefficients.

Formulation ** r24*n
Zero orderFirst orderHiguchi3*Log k

UF-3 gel0.99610.88430.97920.73270.7574
UF-30.97420.79310.95340.81430.8304
Carbopol gel0.82270.99640.93460.99230.9953
Plain drug0.60810.95820.86871.24651.2314

∗∗Coefficient of correlation, 3kinetic constant, and 4diffusional exponent indicative of the mechanism of drug release.