Table 2: Pharmacokinetic characteristics of gliclazide from 18 volunteers following a single oral administration of 30 mg gliclazide MR tablets under fasted condition.

Pharmacokinetic parameterProducts
Test product
(Glycon MR)
Reference product
(Diamicron MR)

(h)8.22 ± 3.957.72 ± 1.96
(ng/mL)1,016.66 ± 283.48898.67 ± 224.45
(ng·h/mL)27,305.13 ± 10811.9025,224.32 ± 11244.21
(ng·h/mL)30,172.13 ± 13609.3228,003.82 ± 13924.33
(h)17.83 ± 5.4015.50 ± 5.69
(h−1)0.04 ± 0.010.04 ± 0.02