Table 4: Pharmacokinetic characteristics of gliclazide from 18 volunteers following a single oral administration of 30 mg gliclazide MR tablets under fed condition.

Pharmacokinetic parameterProducts
Test product
(Glycon MR)
Reference product
(Diamicron MR)

(h)5.56 ± 1.628.11 ± 2.65
(ng/mL)996.48 ± 193.85918.33 ± 207.70
(ng·h/mL)24,338.87 ± 9599.2624,074.37 ± 8885.55
(ng·h/mL)26,969.66 ± 12098.6827,574.71 ± 14049.22
(h)18.14 ± 5.5418.74 ± 7.76
(h−1)0.04 ± 0.010.04 ± 0.01