Table 1: Comparison of donepezil pharmacokinetic parameters after single oral dose of 5 mg reference product (Aricept) and test product (Tonizep).

Pharmacokinetic 
parameter
Reference product 
(Aricept)
Test product 
(Tonizep)

(ng/mL) 18.93 ± 3.8220.42 ± 4.50
(hr) 2.0 (1.0–3.0)2.0 (1.0–3.0)
(ng·hr/mL) 1277.47 ± 328.511375.01 ± 369.01
(hr) 90.7 ± 18.191.5 ± 21.3

1Represented as mean ± SD. 2Represented as median (range).