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Figure 3: Endocrine/metabolic adverse effect profiles. The frequency of reported adverse effects for each drug is given according to the color key. The categories that included a spectrum of symptoms are as follows: thyroid (hyper- or hypothyroidism), blood sugar (diabetes, increased or decreased blood sugar); appetite change (increased or decreased, dysphagia); menstrual change (amenorrhea, dysmenorrheal, early menses, menorrhagia, menstrual cramps, menstrual disorders); sexual dysfunction (erectile dysfunction, delayed ejaculation, impotence, change in libido, priapism).