Table 2: Practical issues involved in clinical implementation of pharmacogenomic testing in healthcare system.

IssueChallenge

Test performanceReasonable turnaround time for delivery of test result
Interpretation of resultNot a straightforward normal versus abnormal interpretation
Education of clinicians is crucial to proper use
Education of health professionalsVariable time and content devoted to educating future clinicians within health professional schools
Overwhelming information for most current practicing clinicians
Cost reimbursement by payersAlmost exclusively based on proof of cost-effectiveness
Acceptance by clinicians Potential additional workload
Potential legal liability
Health disparity concern for patient
Acceptance by patientsPrivacy and discrimination concern
Health disparity concern
Ownership of genetic information