758072.fig.003a
(a) HLA-B27.5(B*2705) (DREDL)
758072.fig.003b
(b) Klebsiella Pul D Secretion protein (DRDEY)
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(c) Klebsiella Nitrogenase (DREDE)
Figure 3: Molecular similarity between HLA-B27 and the nitrogenase reductase peptide of Klebsiella, preventing immune reaction, and dissimilarity with the pullanase peptide (Pul D), of Klebsiella. This explains how HLA-B27 increases the risk of ankylosing spondylitis.