Figure 8: Effect of mevalonate and calmodulin on radioprotection by the GT3-PTX combination. Postirradiation survival study was conducted in mice () treated with GT3, GT3-PTX, GT3-PTX-mevalonate, or GT3-PTX-calmodulin. (a) shows % survival over 30 days in mice treated with 200 mg/kg of GT3 (−24 h), 200 mg/kg of PTX (−15 min) with and without 30mg/kg of mevalonate (−24h). (b) shows % survival over 30 days in mice treated with 200mg/kg of GT3 (−24 h), 200mg/kg of PTX (−15 min) with and without 2000μ/kg of calmodulin (−15min). Calmodulin reduced the % survival () when given in combination with GT3 and PTX. (c) shows the histogram of % survival in various treatment groups at the end of 30 days.