Review Article

Parvovirus B19 Achievements and Challenges

Figure 2

Schematic representation of the left terminal region of B19V and distribution of relevant features. Thick box, left inverted terminal region, and indication of the site of dyad symmetry defining the terminal palindrome. Thin box, contiguous internal unique region. Diamonds highlight the distribution of CpG dinucleotides within sequence. Box and arrow indicate position of TATA box and start of transcription, respectively, as part of the P6 promoter. Black boxes indicate the position of NS protein-binding elements (NSBE 1-4) and a selection of cis-recognition sequences for eukaryotic transcription factors, as indicated.
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