Research Article

Umbilical Serum sHLA-G Levels in Preeclamptic Pregnancies with and without Intrauterine Fetal Growth Restriction: A Comparison with Normotensive Pregnancies with Isolated IUGR and Healthy Controls

Table 1

Analysis of obtained results.

DataThe control group (n = 22)Statistical analysis
Control-IUGR
The IUGR group (n = 7)Statistical analysis
Control-P
The P group
(n = 12)
Statistical analysis
Control-PI
The PI group
(n = 14)

Gravidity1.286 ± 0.561P = 0.5602201.429 ± 0.534P = 0.041323*2.000 ± 1.342P = 0.6131561.429 ± 1.089

Parity1.238 ± 0.436P = 0.3524261.1.429 ± 0.534P = 0.049840*1.818 ± 1.162P = 0.9102061.214 ± 0.802

Maternal age (years)30.200 ± 4.501P = 0.43564528.625 ± 3.182P = 0.73758129.509 ± 6.236P = 0.65418329.493 ± 4.184

Maternal height (cm)166.929 ± 7.457P = 0.670774165.400 ± 3.847P = 0.510086164.600 ± 2.608P = 0.438557164.625 ± 4.502

Maternal weight (kg)81.593 ± 15.537P = 0.63904778.100 ± 7.284P = 0.56582486.450 ± 9.618P = 0.14897391.357 ± 9.983

Maternal BMI (kg/m2)29.175 ± 4.381P = 0.75990728.531 ± 2.238P = 0.09501833.918 ± 2.557P = 0.05334433.348 ± 4.364

Systolic blood pressure (mmHg)117.762 ± 16.266P = 0.874032115.714 ± 13.281P < 0.000001*166.333 ± 13.567P < 0.000001*176.143 ± 16.459

Diastolic blood pressure (mmHg)74.905 ± 10.839P = 0.30185681.429 ± 11.931P = 0.000001*117.083 ± 27.848P < 0.000001*110.857 ± 9.765

Age of gestation (weeks)38.728 ± 0.983P = 0.019867*36.347 ± 4.209P = 0.006425*36.155 ± 3.863P < 0.000001*33.0711 ± 3.880

Birth weight of infant (g)3369.05 ± 403.68P = 0.000021*2179.29 ± 809.83P = 0.054141*2890.91 ± 952.13P < 0.000001*1638.93 ± 702.72

Umbilical sHLA-G levels (Units/mL)17.578 ± 41.136P = 0.93307016.198 ± 20.133P = 0.4227407.778 ± 7.664P = 0.19706137.128 ± 46.972

Data presented as a mean ± SD.
*Statistical significance (P < 0.05).
Groups of studied pregnant women: Control—healthy normotensive pregnant women, IUGR—normotensive women with pregnancy complicated by isolated intrauterine growth restriction, P—preeclamptic women without IUGR, PI—women with IUGR in the course of preeclampsia.