Toxicology Evaluation of Realgar-Containing Niu-Huang-Jie-Du Pian as Compared to Arsenicals in Cell Cultures and in Mice
Figure 3
As accumulation in liver and kidney. Mice were orally given NHJD (600 mg/kg), realgar (600 mg/kg), arsenic disulfide (600 mg/kg), sodium arsenite (36 mg/kg), or sodium arsenate (88 mg/kg). Tissues were collected 8 h later for analysis by atomic fluorescence spectrometry (AFS). Data are mean ± SE of 6 mice and expressed as ng As/g wet tissue. *Significantly different from controls .
