Novel Phenazine 5,10-Dioxides Release ^•OH in Simulated Hypoxia and Induce Reduction of Tumour Volume In Vivo

Figure 2

ESR studies of PDOs in bioreductive system (rat liver cytosolic proteins, 1 mg/mL, +NADPH). ESR spectra of PDOs (1 mM, treated as indicated in Material and methods section) were recorded in presence of the spin trap POBN (100 mM). Number of scans: 15.