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Volume 2011 (2011), Article ID 405813, 6 pages
Th2 Cytokine Levels Distort the Association of IL-10 and IFN- with Allergic Phenotypes
1School of Paediatrics and Child Health, Faculty of Medicine, Dentistry and Health Sciences, The University of Western Australia, GPO Box D184, Perth, WA 6840, Australia
2Telethon Institute for Child Health Research and UWA Centre for Child Health Research, Faculty of Medicine, Dentistry and Health Sciences, The University of Western Australia, GPO Box D184, Perth, WA 6840, Australia
Received 3 November 2011; Accepted 28 November 2011
Academic Editors: D. C. Cara and B. F. Gibbs
Copyright © 2011 Guicheng Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- L. A. Spencer, C. T. Szela, S. A. C. Perez et al., “Human eosinophils constitutively express multiple th1, th2, and immunoregulatory cytokines that are secreted rapidly and differentially,” Journal of Leukocyte Biology, vol. 85, no. 1, pp. 117–123, 2009.
- T. R. Mosmann and R. L. Coffman, “TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties,” Annual Review of Immunology, vol. 7, pp. 145–173, 1989.
- F. Y. Liew, “T(H)1 and T(H)2 cells: a historical perspective,” Nature Reviews Immunology, vol. 2, no. 1, pp. 55–60, 2002.
- G. Del Prete, M. De Carli, F. Almerigogna, M. G. Giudizi, R. Biagiotti, and S. Romagnani, “Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production,” Journal of Immunology, vol. 150, no. 2, pp. 353–360, 1993.
- S. Commins, J. W. Steinke, and L. Borish, “The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29,” Journal of Allergy and Clinical Immunology, vol. 121, no. 5, pp. 1108–1111, 2008.
- K. F. Chung and P. J. Barnes, “Cytokines in asthma,” Thorax, vol. 54, no. 9, pp. 825–857, 1999.
- U. Doshi, P. Salat, and V. Parikh, “Cytokine modulators in asthma: clinical perspectives,” Indian Journal of Pharmacology, vol. 34, no. 1, pp. 16–25, 2002.
- T. R. Mosmann, H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman, “Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins,” The Journal of Immunology, vol. 136, no. 7, pp. 2348–2357, 1986.
- P. Parronchi, M. De Carli, R. Manetti, et al., “IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones,” The Journal of Immunology, vol. 149, no. 9, pp. 2977–2983, 1992.
- J. C. Renauld, “New insights into the role of cytokines in asthma,” Journal of Clinical Pathology, vol. 54, no. 8, pp. 577–589, 2001.
- T. Heaton, J. Rowe, S. Turner et al., “An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children,” Lancet, vol. 365, no. 9454, pp. 142–149, 2005.
- G. Zhang, C. M. Hayden, S. K. Khoo, et al., “Beta2-Adrenoceptor polymorphisms and asthma phenotypes: interactions with passive smoking,” European Respiratory Journal, vol. 30, no. 1, pp. 48–55, 2007.
- S. Young, P. N. Le Souef, G. C. Geelhoed, S. M. Stick, K. J. Turner, and L. I. Landau, “The influence of a family history of asthma and parental smoking on airway responsiveness in early infancy,” The New England Journal of Medicine, vol. 324, no. 17, pp. 1168–1173, 1991.
- L. J. Palmer, P. J. Rye, N. A. Gibson, P. R. Burton, L. I. Landau, and P. N. LeSouëf, “Airway responsiveness in early infancy predicts asthma, lung function, and respiratory symptoms by school age,” American Journal of Respiratory and Critical Care Medicine, vol. 163, no. 1, pp. 37–42, 2001.
- G. Zhang, C. M. Hayden, S. K. Khoo, et al., “Association of haplotypes of beta2-adrenoceptor polymorphisms with lung function and airway responsiveness in a pediatric cohort,” Pediatric Pulmonology, vol. 41, no. 12, pp. 1233–1241, 2006.
- S. L. Prescott, C. Macaubas, T. Smallacombe, B. J. Holt, P. D. Sly, and P. G. Holt, “Development of allergen-specific T-cell memory in atopic and normal children,” Lancet, vol. 353, no. 9148, pp. 196–200, 1999.
- G. Baynam, G. Zhang, S. K. Khoo et al., “Gender-specific effects of cytokine gene polymorphisms on childhood vaccine responses,” Vaccine, vol. 26, no. 29-30, pp. 3574–3579, 2008.
- M. Halonen, I. C. Lohman, D. A. Stern et al., “Th1/Th2 patterns and balance in cytokine production in the parents and infants of a large birth cohort,” Journal of Immunology, vol. 182, no. 5, pp. 3285–3293, 2009.
- G. Zhang, J. Rowe, M. Kusel, et al., “IL-10:IL-5 responses at birth predict risk for respiratory infections in atopic family history,” American Journal of Respiratory and Critical Care Medicine, vol. 179, no. 3, pp. 205–211, 2009.
- A. M. Colavita, A. T. Hastie, A. I. Musani et al., “Kinetics of IL-10 production after segmental antigen challenge of atopic asthmatic subjects,” Journal of Allergy and Clinical Immunology, vol. 106, no. 5, pp. 880–886, 2000.
- M. John, S. Lim, J. Seybold et al., “Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1α, granulocyte-macrophage colony-stimulating factor, and interferon-γ release from alveolar macrophages in asthma,” American Journal of Respiratory and Critical Care Medicine, vol. 157, no. 1, pp. 256–262, 1998.