Promotion of the Toxic Action of Cyclophosphamide by Digestive Tract Luminal Ammonia in Rats

<table>The mean survival time of rats after the gavage with ammonium acetate and (or) the intraperitoneal administration of cyclophosphamide, mean (SEM), <svg height="10.8125" id="M4" style="vertical-align:-0.10033pt" version="1.1" viewbox="0 0 42.912498 10.8125" width="42.912498" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.8125)">
<g transform="translate(72,-63.35)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑛</tspan>
<tspan style="font-size: 12.50px; " x="9.6773224" y="0">=</tspan>
<tspan style="font-size: 12.50px; " x="21.71771" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="27.969212" y="0">1</tspan>
</text>
</g>
</g>
</svg>. Open circles: sodium acetate + cyclophosphamide (the control group); closed circles: ammonium acetate + cyclophosphamide. Significantly different with the control group: (*) <svg height="12.4875" id="M5" style="vertical-align:-1.29163pt" version="1.1" viewbox="0 0 56.150002 12.4875" width="56.150002" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.4875)">
<g transform="translate(72,-62.01)">
<text transform="matrix(1,0,0,-1,-71.95,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">≤</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">5</tspan>
</text>
</g>
</g>
</svg>.</table>

International Scholarly Research Notices

fig2

Figure 2

Figure 2: Promotion of the Toxic Action of Cyclophosphamide by Digestive Tract Luminal Ammonia in Rats 