Clinical Study

Clinical and Morphologic Differences between Class IV-S and Class IV-G Lupus Nephritis

Table 4

Comparison of some laboratory and clinical parameters in patients with class IV segmental (S) versus global (G) proliferative lupus nephritis (LN).

ParameterClass IV-S LNClass IV-G LN 𝑃

Proteinuria (g/24 h)3,22 ± 2,26 (0,41–10,50)5,54 ± 4,69 (0,32–15,54) 𝑃 < 0,05
Serum albumin (g/L)35,07 ± 7,27 (19–47)29,82 ± 6,25 (21–44) 𝑃 < 0,01
Serum total protein (g/L)63,08 ± 8,46 (28–75)56,27 ± 8,52 (38–73) 𝑃 < 0,05
Serum creatinine (μmoL/L)114,0 ± 64,14 (67–348)185,2 ± 138,7 (70–540) 𝑃 < 0,05
Haemoglobin (g/L)115,9 ± 12,48 (78–136)102,8 ± 13,64 (84–130) 𝑃 < 0,001
C3 complement (g/L)0,88 ± 0,12 (0,67–1,25)0,77 ± 0,06 (0,64–0,89) 𝑃 > 0,05
Number (%) of patients with arterial hypertension24 (58,54%)22 (100%) 𝑃 < 0,05
Diastolic blood pressure (mean values)96,42 ± 13,12 mmHg104,12 ± 10,45 mmHg 𝑃 < 0,02