Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats

Table 2

Effect of Hypericum perforatum on plasma glucose, insulin, and body weight gain in fructose-fed rats.

Group (𝑛=6)	Glucose (mg/dL)	Plasma insulin (μIU/mL)	Body weight gain (g)
Normal control; (normal drinking water + CMC)	80.52 ± 3.44	18.05 ± 0.79	12.33 ± 1.05
Fructose control (fructose + CMC)	149.66 ± 4.49**	35.03 ± 1.24**	26.83 ± 2.59**
Normal drinking water + HpE 100 mg/kg	82.53 ± 3.35^††	19.37± 0.95^††	11.50 ± 1.48^††
Normal drinking water + HpE 200 mg/kg	78.18 ± 1.71^††	20.29 ± 0.78^††	11.83 ± 1.30^††
Fructose + HpE 100 mg/kg	125.44 ± 5.70^** †	32.32 ± 1.10**	21.00 ± 3.62*
Fructose + HpE 200 mg/kg	105.15 ± 3.88^** ††	30.58 ± 0.83^** †	20.17 ± 2.17*

^∗𝑃<.05,^∗∗𝑃<.001 versus normal control; ^†𝑃<.01,^††𝑃<.001 versus fructose control.