Research Article
Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats
Table 2
Effect of Hypericum perforatum on plasma glucose, insulin, and body weight gain in fructose-fed rats.
| Group | Glucose (mg/dL) | Plasma insulin (μIU/mL) | Body weight gain (g) |
| Normal control (normal drinking water + CMC) | 80.52 ± 3.44 | 18.05 ± 0.79 | 12.33 ± 1.05 | Fructose control (fructose + CMC) | 149.66 ± 4.49** | 35.03 ± 1.24** | 26.83 ± 2.59** | Normal drinking water + HpE 100 mg/kg | 82.53 ± 3.35 †† | 19.37± 0.95†† | 11.50 ± 1.48†† | Normal drinking water + HpE 200 mg/kg | 78.18 ± 1.71†† | 20.29 ± 0.78†† | 11.83 ± 1.30†† | Fructose + HpE 100 mg/kg | 125.44 ± 5.70** † | 32.32 ± 1.10** | 21.00 ± 3.62* | Fructose + HpE 200 mg/kg | 105.15 ± 3.88** †† | 30.58 ± 0.83** † | 20.17 ± 2.17* |
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versus normal control; versus fructose control.
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