Research Article

Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats

Table 5

Effect of Hypericum perforatum on plasma glucose and insulin in high-fat-induced obese rats.

Group ( 𝑛 = 6 ) Glucose (mg/dL)Plasma insulin (μIU/mL)

Normal control
(NPD + CMC)
84.96 ± 3.5816.61 ± 0.86
HFD control
(HFD + CMC)
130.89 ± 3.70**62.14 ± 2.95**
HFD + HpE 100 mg/kg112.15 ± 3.08**†36.47 ± 2.25**†
HFD + HpE 200 mg/kg98.89 ± 3.01*†28.78 ± 1.53**†

𝑃 < . 0 1 , 𝑃 < . 0 0 1 versus normal control; 𝑃 < . 0 0 1 versus HFD control.