Pharmacokinetic Compatibility Study of Lidocaine with EXPAREL in Yucatan Miniature Pigs
Figure 3
Mean systemic exposure parameters (±SD) for plasma lidocaine (a) and bupivacaine (b) after high (4 mg/kg) subcutaneous dose of lidocaine/epinephrine and EXPAREL (/group unless noted). Series 1: (ng/mL·hr). Series 2: (ng/mL). Notes: SD was not calculated for mean plasma bupivacaine concentrations at 5 minutes () because one animal received 55% of the intended dose of EXPAREL; therefore, data from this animal were not used in calculation of means; individual values for = 2,980 and 5,770 ng/mL·hr and for = 3,690 and 7,770 ng/mL.
