Pharmacokinetic Compatibility Study of Lidocaine with EXPAREL in Yucatan Miniature Pigs

Figure 5

Systemic exposure parameters (±SD) for plasma bupivacaine after high (4 mg/kg) subcutaneous dose of lidocaine/epinephrine and EXPAREL (𝑁=3/group unless noted). Notes: SD was not calculated for bupivacaine at 5 minutes (𝑁=2, AUC = 2,980 and 5,770 ng/mL·h; 𝐶_max = 3,690 and 7,770 ng/mL).