Review Article

Review of Breast Conservation Therapy: Then and Now

Table 2

Sorlie molecular subtypes and response to neoadjuvant chemotherapy [50, 51, 59].

Sorlie subtypeReceptor correlatesEstimated pCR rates

Luminal AHR+, Her2−7–12%
Luminal BHR+, Her2+15–25%
Her2-likeHR−, Her2+20–25% (without Herceptin)
40–60% (with Herceptin)
BasalHR−, Her2−25–55%