Dementia Enhances Inhibitory Actions of General Anesthetics in Hippocampal Synaptic Transmission

Figure 3

Effects of sevoflurane (3.0 vol%) and thiopental (10⁻⁵ mol/L) on the peak amplitude of population spike in the recurrent inhibition enhanced (RIE) circuit in dementia model mice (SAM-P8, 𝑛=5) and control mice (SAM-R1, 𝑛=5). Data were expressed as % of control (mean ± SD). ^∗𝑃<0.05.