Research Article

Studies on Wound Healing Activity of Heliotropium indicum Linn. Leaves on Rats

Table 5

Screening for wound healing activity of the methanol extract of the selected plants (excision wound model) by inoculated with P. aeruginosa.

Group TreatmentPercentage (%) wound closurePeriod of epithelialization (no. of days)
4th days6th days8th days11th days14th days16th days

IControl8.22 ± 1.8115.6 ± 1.2221.08 ± 2.7132.41 ± 3.3346.61 ± 3.8551.13 ± 2.1530.33 ± 2.23
IINitrofurazone (0.2% w/w)14.21 ± 1.0925.73 ± 3.81*39.43 ± 2.22**57.63 ± 3.11**78.56 ± 2.48**92.53 ± 3.25**18.73 ± 1.81**
IIIMethanol extract (HI)12.5 ± 1.2521.5 ± 2.8132.26 ± 2.14*49.6 ± 2.18**70.22 ± 3.81**84.26 ± 2.55**20.10 ± 0.48*

Values are expressed as mean ± S.E. ( 𝑛 = 6 ). All columns are significant using ANOVA.
* 𝑃 < . 0 5 , ** 𝑃 < . 0 1 when compared to control; Dunnet’s 𝑡 -test. (HI-H. indicum).