Review Article
Systemic Lupus Erythematosus: Recent Concepts in Genomics, Pathogenetic Mechanisms, and Therapies
Table 3
Distribution of genes implicated in the causation of SLE between ethnic groups (adapted from [
3]).
| Characteristics of the genes | Genes |
| Consistent association with similar frequency between different ethnic groups | STAT4 | TNFAIP3 | BANK1 | IRAK1 | MECP2 |
| Consistent association with different allele frequency between various ethnic groups | BLK | IRF5 |
| Allelic heterogeneity | HLA-DRB1 | FcGRs | IRF5 |
| Genetic heterogeneity | PTPN22 | ITGAM | PXK | LYN |
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