Table 3: Distribution of genes implicated in the causation of SLE between ethnic groups (adapted from [3]).

Characteristics of the genesGenes

Consistent association with similar frequency between different ethnic groupsSTAT4
TNFAIP3
BANK1
IRAK1
MECP2

Consistent association with different allele frequency between various ethnic groupsBLK
IRF5

Allelic heterogeneityHLA-DRB1
FcGRs
IRF5

Genetic heterogeneityPTPN22
ITGAM
PXK
LYN