Research Article

Heart Rate Variability in HIV Patients, Diabetics, and Controls: The AGATAA Study

Table 1

General characteristics and cardiovascular risk factors in the participants of the study including HIV people using or not treatment with HAART, diabetic, and controls.

HAART 𝑁 = 2 9 (%) Naïve 𝑁 = 2 8 Diabetes 𝑁 = 4 4 (%)Controls 𝑁 = 3 0 (%) 𝑃 p

Age a (years)43.6 (8.6) e 42.0 (6.7) f 49.1 (5.7) e , f , g 42.4 (7.9) g <0.0001
Women (%)9 (31)10 (35.7)23 (52.3)14 (46.7)0.26
Body Mass Index (kg/m2)25.8 (3.8) h 26.2 (4.9) i 30.6 (4.8) h , i 29.3 (10.8)0.005
Rest Heart rate (beats/min)72.1 (10.4)69.7 (10.8)73.9 (11.9)68.8 (16.1)0.30
Waist circumference (cm)90.4 (10.8) j 86.9 (11.4) k 99.5 (10.3) j , k , l 89.2 (13.9) g <0.0001
Waist to hip ratio0.9 (0.9) m 0.9 (0.8)0.9 (0.7) n 0.9 (0.7) m , n <0.0001
Systolic blood pressure (mm Hg) a 124.7 (13.2)118.1 (14.4) o 127.8 (12.4) o 119.7 (15.7)0.01
Study years0.34
 0 (%)1 (3.4)0 (0)1 (2.3)0 (0)
 1–8 years (%)4 (10.7)7 (25.0)4 (9.4)6 (20.0)
 9–11 years (%)12 (41.3)11 (39.2)24 (55.8)3 (40.0)
 >11 years (%)12 (41.3)10 (35.7)12 (39.9)12 (40.0)
Race0.65
 White13 (44.8)14 (50.0)23 (52.3)13 (43.3)
 Mixed10 (34.5)12 (42.9)14 (31.8)14 (46.7)
 Black5 (17.2)2 (7.1)7 (15.9)3 (10.0)
 Others1 (3.4)0 (0)0 (0)0 (90)
Smoking
 Current (%)7 (38.9)6 (42.9)9 (30.0)5 (33.3)0.84
High blood pressure (mm Hg) (%) b 12 (41.4)8 (28.6)36 (81.8)8 (26.7)<0.0001
Diabetes (%) c 5 (17.2)1 (3.6)44 (100)0 (0)<0.0001
Dislipidemia (%) d 27 (93.1)23 (82.1)36 (83.7)22 (73.3)0.25

HAART: highly active antiretroviral therapy.
a Mean (standard deviation); b High blood pressure defined by self-report medical history of hypertension or current treatment for hypertension or systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg; c Diabetes defined by self-report medical history of diabetes or current treatment for diabetes or a 120 minutes glucose test ≥200 mg/dL; d Dislipidemia defined as self-reported medical history of dislipidemia or current treatment for dislipidemia or LDL-cholesterol ≥130 mg/dL, HDL-cholesterol ≤40 mg/dL or triglycerides ≥150 mg/dL.
e Group HAART Group diabetes, 𝑃 < 0 . 0 0 9 ; f Group naïve Group diabetes, 𝑃 < 0 . 0 0 0 1 ; g Group diabetes Group control, 𝑃 = 0 . 0 0 1 ; h Group HAART Group diabetes, 𝑃 = 0 . 0 1 ; i Group naïve Group diabetes, 𝑃 = 0 . 0 4 ; j Group HAART Group diabetes, 𝑃 < 0 . 0 0 7 ; k Group naïve Group diabetes, 𝑃 < 0 . 0 0 0 1 ; l Group diabetes Group control, 𝑃 = 0 . 0 0 1 ; m Group HAART Group control, 𝑃 = 0 . 0 0 3 ; n Group diabetes group control, 𝑃 < 0 . 0 0 2 ; o group naïve group diabetes, 𝑃 < 0 . 0 3 .
p 𝑃 values for differences among the four categories applying F-test for continuous variables and or Chi-square for categorical variables.