International Scholarly Research Notices

Research Article

Heart Rate Variability in HIV Patients, Diabetics, and Controls: The AGATAA Study

Table 2

Median (interquartile interval) of the time and frequency domain indices of heart rate variability in HIV-infected patients (treated or not treated with HAART), diabetics, and controls.


	HAART (%)	Naïve	Diabetes (%)	Controls (%)

		Time Index

R-R Interval (m/s)	903.1 (758.9–959.5)	908.1 (771.1–1007.5)	883.2 (755.0–933.3)	844.3 (797.1–914.8)	0.55
SDNN (m/s)	26.9 (34.2–64.3)	45.6 (33.0–72.5)	39.1 (25.5–42.7)	45.6 (32.3–62.3)	0.059
pNN50 (%)	3.1 (0.6–11.0)	5.4 (1.0–28.5)	3.4 (0.9–12.0)	7.7 (1.6–20.4)	0.32
r-MSSD (ms)	26.2 (18.5–48.8)	36.5 (25.4–69.2)	25.8 (17.8–40.3)	30.7 (219.2–43.7)	0.36

Low frequency spectral area (ms²)	45.8 (23.1–60.1)	42.2 (33.2–68.2)	25.8 (17.8–40.3)	60.3 (40.3–73.3)	0.06
High frequency spectral area (ms²)	46.2 (31.2–74.1)	47.5 (29.5–60.4)	50.1 (42.1–67.9)	29.5 (21.8–58.2)	0.06
Normalized low frequency area	46.1 (30.6–62.0)	39.9 (28.5–65.7)	42.9 (14.5–57.7)	67.5 (37.9–75.4)	0.04
Normalized high frequency area	45.3 (30.6–67.2)	49.7 (30.4–64.8)	53.5 (34.5–72.2)	27.0 (19.0–57.3)	0.03
LF/HF area	1.1 (0.3–1.7)	0.8 (0.6–2.3)	0.9 (0.3–1.4)	2.3 (0.8–3.3)	0.04

HAART: highly active antiretroviral therapy; SDNN: standard deviation of all NN intervals; pNN50: the proportion derived by a division of the number of pairs of adjacent NN intervals differing by more than 50 ms in the entire recording by the total number of all NN intervals; r-MSSD, the square root of the mean of sum of the squares of differences between adjacent NN intervals; LF: low frequency; HF: high frequency.
values for differences among the four categories applying F-test for continuous variables and or Chi-square for categorical variables.
*Median (interquartile interval);
diabetics ≠ controls, ; diabetics ≠ controls, ; naïve ≠ controls, ; diabetics ≠ controls, ; naïve ≠ controls, ; diabetics ≠ controls, ; naïve ≠ controls, ; diabetics ≠ controls, .