Optic Nerve and Spinal Cord Are the Major Lesions in Each Relapse of Japanese Multiple Sclerosis
Figure 2
(a) Sex ratio of each localization of MS attacks. Half of the brainstem lesions occurred in males, although there was a remarkable female predominancy for other lesion sites. (b) Age at attack for each localization of MS attacks. Mean age at brainstem attack was 29.6 ± 6.0 years old and is significantly younger than the mean age at optic nerve attack (42.5 ± 14.4 y.o.) and spinal cord attack (42.6 ± 13.6 y.o.) using Welch’s t-test (P < 0.05). Regarding other lesions, mean patient age at attacks involving the cerebrum was 42.3 ± 13.5 y.o., and the mean age at the development of complex lesions was 38.7 ± 10.9 y.o. Boxes represent values from the 25th to the 75th percentiles, inner lines represent the median, and whiskers show the minimal and maximal values.
