Research Article
Immunorecognition of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Some Normal and Malignant Tissues from Genitourinary System
Table 2
Immunorecognition of 14F7 Mab in primary tumors of urinary and male genital systems.
| | Histopathological type | No. of cases (%) | Intensity range | Positive cells |
| | Kidney | 12/38 (31.6) | | | | Benign | | | | | (i) Renal oncocytoma | 1/2 (50) | + | 3 | | Malignant | | | | | (i) Renal cell carcinoma | 11/36 (30.5) | | | | (a) Clear cell renal carcinoma | 7/28 (25) | ++/+++ | 2 | | (b) Papillary renal carcinoma | 3/6 (50) | ++/+++ | 3 | | (c) Chromophobe renal carcinoma | 0/1 | − | 0 | | (d) Collecting duct carcinoma | 1/1 | +++ | 3 | | Bladder | 8/9 (88.8) | | | | (i) Transitional cell carcinoma (I) | 2/2 | +/+++ | 3 | | (ii) Transitional cell carcinoma (II) | 3/3 | ++/+++ | 3 | | (ii) Transitional cell carcinoma (III) | 3/4 (75) | +++ | 3 | | Prostate | 22/28 (78.6) | | | | (i) Nodular hyperplasia | 5/8 (62.5) | +/++/+++ | 1/3 | | (ii) Adenocarcinoma | 17/20 (85) | | | | (a) Well differentiated | 13/15 (86.6) | +/++/+++ | 3 | | (b) Moderately differentiated | 3/4 (75) | +++ | 3 | | (c) Poorly differentiated | 1/1 | Heterogeneous | 1 | | Testis | | | | | Classic seminoma | 4/5 (80) | ++/+++ | 2/3 |
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Intensity: −: negative, ++: moderate, +++: intense. Positive cells: 0 (negative to less than 5%), 1 (6–25%), 2 (26–50%), and 3 (more than 50%).
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