Research Article

Spatially Explicit Nonlinear Models for Explaining the Occurrence of Infectious Zoonotic Diseases

Table 3

Model summary statistics for spatially explicit models describing the occurrence of medically diagnosed cases of Lyme disease and Rocky Mountain spotted fever for the 2000–09 study period within Tennessee.

Model typeLyme disease (LD)Rocky mountain spotted fever (RMSF)
GBTSLRNNETCARTGBTSLRNNETCART

Model performance
 Misclassification rate0.232*0.2720.2880.2960.3040.3120.288*0.296
 Average square error0.1870.1820.2530.2060.2300.2100.2320.213
 ROC0.7890.8120.6880.6740.7020.7270.6960.712
 PPV83.7%75.0%77.1%85.7%69.8%68.5%72.5%70.4%
 Sensitivity66.1%67.7%59.7%48.4%62.7%62.7%62.7%64.4%
 Specificity87.3%77.8%82.5%92.1%75.8%74.2%78.8%75.8%
Input variables**
 Land cover
  Forested wetland+/−++/−
  Nonforested wetland+/−
  Pasture/grassland++/−+/−+
  Upland deciduous forest+/−+/−
  Urban/developed+++++/−
 Wetland type
  PUBHh
 Geographic
  Distance to river+/−
 Demographic
  Population counts++++++++/−
  Median income+++/−+
 Clinical
  Lyme Dis. cooccurrence++++
  RMSF cooccurrence++++

*Best model chosen using lowest misclassification rate on validation dataset.
**Denotes that aggregations were made at 1.6 and 8 km where applicable.
Variables missing from this table indicate nonsignificance across all models, and plus and minus signs indicate direction of relationship.