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International Scholarly Research Notices
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International Scholarly Research Notices
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2012
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Article
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Fig 6
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Review Article
General Aspects of Colorectal Cancer
Figure 6
Hedgehog pathway. In absence of Hedgehog (Hh), PTCH1 binds to SMO, whereas in presence of Hh, the complex Hh-PTCH1 internalizes and releases SMO. Free SMO activates a family of transcription factors, including GLI (adapted from [
75
]).