Low-Dose Chemotherapy with Insulin (Insulin Potentiation Therapy) in Combination with Hormone Therapy for Treatment of Castration-Resistant Prostate Cancer

Table 1

Clinical characteristics of the treated patients.

Clinical parameters	Group A	Group B
Total number of patients	8	8
Age
Median	64	66
Range	56–76	53–73
Karnovsky performance scale (mean)
Median	68	74
Range	50–80	60–90
Beretta score before treatment
Median	24	24
Range	10–42	6–33
Glison score
4	1	0
5	1	1
6	0	1
7	2	1
8	1	0
9	3	3
Unknown	0	2
Tumor stage
Stage III	0	0
Stage IV	8	8
Extend of disease (nr.)
With local metastases	3 (8)	3 (8)
With distant metastases	7 (8)	7 ( 8)
Previous therapy
Surgical orchiectomy	6 (8)	5 (8)
Antiandrogens	8 (8)	7 (8)
Palliative radiotherapy	4 (8)	0
PSA(ng/mL)
Median	389,6	1511,2
Range	63,3–1320	17,16–8395
Al. phosphatase mg/mL
Median	1673	1120
Range	246–4286	253–5264