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ISRN Nanotechnology
Volume 2012 (2012), Article ID 187354, 9 pages
http://dx.doi.org/10.5402/2012/187354
Research Article

Encapsulation of Berberine in Nano-Sized PLGA Synthesized by Emulsification Method

1Department of Chemistry, Momin College, Maharashtra, Bhiwandi, India
2N.S.N. Research Centre for Nanotechnology & Bionanotechnology, Jambhul Phata, Maharashtra, Ambernath 421 505, India

Received 30 April 2012; Accepted 17 July 2012

Academic Editors: Y. I. Jeong, C. Li, and P. Perriat

Copyright © 2012 Manisha Khemani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. F. Liu, “DNA topoisomerase poisons as antitumor drugs,” Annual Review of Biochemistry, vol. 58, pp. 351–375, 1989. View at Scopus
  2. I. Bala, S. Hariharan, and M. N. V. R. Kumar, “PLGA nanoparticles in drug delivery: The state of the art,” Critical Reviews in Therapeutic Drug Carrier Systems, vol. 21, no. 5, pp. 387–422, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. O. Kucuk, “Chemoprevention of prostate cancer,” Cancer and Metastasis Reviews, vol. 21, no. 2, pp. 111–124, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Barnes, “Role of phytochemicals in prevention and treatment of prostate cancer,” Epidemiologic Reviews, vol. 23, no. 1, pp. 102–105, 2001. View at Scopus
  5. J. Cheng, B. A. Teply, I. Sherifi et al., “Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery,” Biomaterials, vol. 28, no. 5, pp. 869–876, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. G. V. Sathyavathi, A. K. Gupta, N. Tandon, et al., Medicinal Plants of India, vol. 2, Indian Council of Medical Research, New Delhi, India, 1987.
  7. K. Fukuda, Y. Hibiya, M. Mutoh, M. Koshiji, S. Akao, and H. Fujiwara, “Inhibition of activator protein 1 activity by berberine in human hepatoma cells,” Planta Medica, vol. 65, no. 4, pp. 381–383, 1999. View at Scopus
  8. J. G. Lin, J. G. Chung, and L. T. Wu, “Effects of berberine on arylamine Nacetyl-transferase activity in human colon tumor cells,” The American Journal of Chinese Medicine, vol. 27, pp. 265–275, 1999.
  9. K. Fukuda, Y. Hibiya, M. Mutoh, M. Koshiji, S. Akao, and H. Fujiwara, “Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells,” Journal of Ethnopharmacology, vol. 66, no. 2, pp. 227–233, 1999. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Szeto, C. M. N. Yow, and K. W. Fung, “Characterization of berberine on human cancer cells in culture,” Turkish Journal of Medical Sciences, vol. 32, no. 5, pp. 363–368, 2002. View at Scopus
  11. A. M. Roy, M. S. Baliga, C. A. Elmets, and S. K. Katiyar, “Grape seed proanthocyanidins induce apoptosis through p53, bax, and caspase 3 pathways,” Neoplasia, vol. 7, no. 1, pp. 24–36, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Ahlin, J. Kristl, A. Kristl, and F. Vrečer, “Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration,” International Journal of Pharmaceutics, vol. 239, no. 1-2, pp. 113–120, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Jalil and J. R. Nixon, “Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: Problems associated with preparative techniques and release properties,” Journal of Microencapsulation, vol. 7, no. 3, pp. 297–325, 1990. View at Scopus
  14. C. H. Chang, W. Y. Huang, C. H. Lai et al., “Development of novel nanoparticles shelled with heparin for berberine delivery to treat Helicobacter pylori,” Acta Biomaterialia, vol. 7, no. 2, pp. 593–603, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. L. I. N. Aihua, L. I. Hongyan, L. I. U. Yiming, and Q. I. U. Xiaohui, “Preparation and release characteristics of berberine chitosan nanoparticles in vitro,” China Pharmacy, 2007.
  16. Z.-H. Zhang, Y.-S. Sun, H. Pang, W. L. L. Munyendo, H.-X. Lv, and S.-L. Zhu, “Preparation and evaluation of berberine alginate beads for stomach-specific delivery,” Molecules, vol. 16, no. 12, pp. 10347–10356, 2011. View at Publisher · View at Google Scholar · View at Scopus