Clinical Study

High-Dose Therapy and Autologous Hematopoietic Progenitor Cells Transplantation for Recurrent or Refractory Hodgkin's Lymphoma: Analysis of King Hussein Cancer Center Results and Prognostic Variables

Table 1

Characteristics of 63 patients with HL who underwent autologous stem cell transplantation.

Count (%)

GenderMale38 (60.3%)
Female25 (39.7%)
AgeAdult54 (85.7%)
Pediatric9 (14.3%)
Number of previous Chemotherapy lines received2 lines35 (55.6%)
>2 lines28 (44.4%)
Disease status at transplantComplete remission16 (25.4%)
Responsive disease45 (71.4%)
Stable disease2 (3.2%)
Time to relapse (TTR)≤12 months30 (48%)
>12 months33 (52%)
Mobilization regimenChemotherapy + GCSF57 (90.5%)
GCSF only6 (9.5%)
Stem cell sourcePeripheral63 (100%)
Stem cell doseMedian (range)5.6 × 1 0 6 / k g
(1.51−12.1 × 1 0 6 / k g )
Conditioning regimenBEAM*60 (95.2%)
TEAM**2 (3.2%)
CBV***1 (1.6%)

*BEAM: BCNU, etoposide, Ara-C, melphalan.
**TEAM: thiotepa, etoposide, Ara-C, melphalan.
***CBV: cyclophosphamide, BCNU, VP16.