PP13 and PAPP-A in the First and Second Trimesters: Predictive Factors for Preeclampsia?

Table 4

Validity of studied markers for preeclampsia in the first and second trimesters.

Marker	Cutoff	Sensitivity; (95% CI)	Specificity %; (95% CI)	Positive predictive value %; (95% CI)	Negative predictive value %; (95% CI)	Surface under curve; (95% CI)
PAPPA first trimester	≤1.65	60.0; (49.7–69.7)	78.0; (68.6–85.7)	73.2; (62.2–82.4)	66.1; (56.8–74.6)	0.793; (0.733–0.854)
PP13 first trimester	≤88.5	77.0; (67.5–84.8)	82.0; (73.1–89.0)	81.1; (71.7–88.4)	78.1; (69.0–85.6)	0.879; (0.833–0.924)
PAPPA second trimester	≤100.5	71.0; (61.1=79.6)	71.0; (61.1=79.6)	71.0; (61.1=79.6)	71.0; (61.1=79.6)	0.809; (0.751–0.867)
PP13 second trimester	≤315.5	79.0; (69.7–86.5)	80.0; (70.5–87.3)	79.8; (70.5–87.2)	79.2; (70.0–86.6)	0.876; (0.829–0.924)