PP13 and PAPP-A in the First and Second Trimesters: Predictive Factors for Preeclampsia?

Table 8

Validity factors in parallel tests of preeclampsia markers based on the first and second trimesters.

Time session	Positive result	Sensitivity; (95% CI)	Specificity %; (95% CI)	Positive predictive value %; (95% CI)	Negative predictive value %; (95% CI)
First trimester	Both positive	51.0; (40.8–61.1)	96.0; (90.1–98.9)	92.7; (82.4–98.0)	66.2; (57.8–73.8)
First trimester	At least one positive	86.0; (77.6–92.1)	64.0; (53.8–73.4)	70.5; (61.6–78.4)	82.1; (71.1–89.8)
Second trimester	Both positive	56.0; (45.7–65.9)	97.0; (91.5–99.4)	94.9; (85.9–98.9)	68.8; (60.5–76.3)
Second trimester	At least one positive	94.0; (87.4–97.8)	54.0; (43.7–74.8)	67.1; (58.7–74.8)	90.0; (79.5–96.2)