Stability-Indicating High-Performance Thin-Layer Chromatographic Method for Quantitative Estimation of Emtricitabine in Bulk Drug and Pharmaceutical Dosage Form

<table>Densitogram of base-treated emtricitabine 1000 ng spot<sup>−1</sup>; condition: 0.01 N NaOH 80°C for 3.5 h; Peak 1, 2, 4 (degraded, <svg height="16.2875" id="M46" style="vertical-align:-4.77652pt" version="1.1" viewbox="0 0 19.700001 16.2875" width="19.700001" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,16.2875)">
<g transform="translate(72,-58.97)">
<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑅</tspan>
</text>
<text transform="matrix(1,0,0,-1,-62.7,60.66)">
<tspan style="font-size: 8.75px; " x="0" y="0">𝑓</tspan>
</text>
</g>
</g>
</svg>: 0.03, 0.07, 0.71), Peak 3 (emtricitabine, <svg height="16.2875" id="M47" style="vertical-align:-4.77652pt" version="1.1" viewbox="0 0 19.700001 16.2875" width="19.700001" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,16.2875)">
<g transform="translate(72,-58.97)">
<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑅</tspan>
</text>
<text transform="matrix(1,0,0,-1,-62.7,60.66)">
<tspan style="font-size: 8.75px; " x="0" y="0">𝑓</tspan>
</text>
</g>
</g>
</svg>: 0.26).</table>

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fig7

Figure 7

Figure 7: Stability-Indicating High-Performance Thin-Layer Chromatographic Method for Quantitative Estimation of Emtricitabine in Bulk Drug and Pharmaceutical Dosage Form 

Figure 7 | Stability-Indicating High-Performance Thin-Layer Chromatographic Method for Quantitative Estimation of Emtricitabine in Bulk Drug and Pharmaceutical Dosage Form 