Stability-Indicating High-Performance Thin-Layer Chromatographic Method for Quantitative Estimation of Emtricitabine in Bulk Drug and Pharmaceutical Dosage Form

<table>Densitogram of H<sub>2</sub>O<sub>2</sub>-treated emtricitabine 1000 ng spot<sup>−1</sup><sub>;</sub> condition: 3% H<sub>2</sub>O<sub>2</sub> at room temperature for 8 h; Peak 1, 3 (degraded, <svg height="16.2875" id="M49" style="vertical-align:-4.77652pt" version="1.1" viewbox="0 0 19.700001 16.2875" width="19.700001" xmlns="http://www.w3.org/2000/svg">
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<g transform="translate(72,-58.97)">
<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑅</tspan>
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</svg>: 0.07, 0.43), Peak 2 (emtricitabine, <svg height="16.2875" id="M50" style="vertical-align:-4.77652pt" version="1.1" viewbox="0 0 19.700001 16.2875" width="19.700001" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,16.2875)">
<g transform="translate(72,-58.97)">
<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑅</tspan>
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</svg>: 0.23).</table>

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fig8

Figure 8

Figure 8: Stability-Indicating High-Performance Thin-Layer Chromatographic Method for Quantitative Estimation of Emtricitabine in Bulk Drug and Pharmaceutical Dosage Form 

Figure 8 | Stability-Indicating High-Performance Thin-Layer Chromatographic Method for Quantitative Estimation of Emtricitabine in Bulk Drug and Pharmaceutical Dosage Form 